In ancient times only the northern part of the region was called Apulia; the southern peninsula was known as Calabria, a name later used to designate the "toe" of the Italian "boot."
One of the richest in Italy for archeological findings, the region was settled from the 1st millennium BC by several Illyric and Italic peoples. Later, the Greeks expanded until reaching the area of Taranto and the Salento. In the fifth and fourth centuries BC, the Greek settlement at Taras produced a distinctive style of pottery (Apulian vase painting).
Apulia was an important area for the ancient Romans, who conquered it during the course of wars against the Samnites and against Pyrrhus in the fourth and third centuries B.C.
in the 4th century BC but also suffered a crushing defeat here in the battle of Cannae against Hannibal. However, after the Carthaginians left the region, the Romans captured the ports of Brindisi and Taranto, and established dominion over the region. During the Imperial age Apulia was a flourishing area for production of grain and oil, becoming the most important exporter to the Eastern provinces.
After the fall of Rome, Apulia was held successively by the Goths, the Lombards and, from the 6th century onwards, the Byzantines. Bari became the capital of a province that extended to modern Basilicata, and was ruled by a catepano (governor), hence the name of Capitanata of the Barese neighbourhood. From 800 on, Saracen domination in the area was intermittent, but Apulia was mostly under Byzantine authority until the 11th century, when the Normans conquered it with relative ease.
Robert Guiscard set up the duchy of Apulia in 1059. After the Norman conquest of Sicily in the late 11th century, Palermo replaced Melfi (just west of present day Apulia) as the center of Norman power, and Apulia became a mere province, first of the Kingdom of Sicily, then of the Kingdom of Naples. From the late 12th to early 13th centuries, Apulia was a favorite residence of the Hohenstaufen emperors, notably Frederick II. After the fall of the latter's heir, Manfred, under the Angevine and Aragonese/Spanish dominations Apulia became largely dominated by a small number of powerful landowners (Baroni). In 1734 there were the battle of Bitonto, a Spanish victory over Austrian forces. The coast was occupied at times by the Turks and by the Venetians. The French also controlled the region in 1806-1815, resulting in the abolition of feudalism and the reformation of the justice system.
Liberation movements began to spread in the 1820s. In 1861, with the fall of Two Sicilies, the region joined Italy. Social and agrarian reforms that had proceeded slowly from the 19th century accelerated in the mid-20th century.
The characteristic Apulian architecture of the 11th–13th centuries reflects Greek, Arab, Norman, and Pisan influences. Universities are located in Bari, Lecce and Foggia.